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Canada Goose Outlet The move could pressure rivals such as Pfizer Inc to lower prices for existing hemophilia treatments, which provide patients with life saving infusions of a blood clotting agent, according to doctors and industry analysts. and Canadian approval for Alprolix to treat hemophilia B, the more rare form of the condition that affects about 4,000 people in the United States and about 25,000 worldwide. Canada Goose Outlet
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Canada Goose Jackets FACTORS IN PRICING BIOGEN Kingsley said Biogen had been discussing the pricing for its new hemophilia drug prior to the furor over Sovaldi. But it would appear that the company has taken cheap Canada Goose public perception of the new medicine cost into consideration. Biogen Chief Executive George Scangos had signaled earlier this year that if he believed Alprolix was likely to be perceived as more Canada Goose Outlet of an advance in convenience than efficacy, it would probably be priced on a par with existing treatments. approval decision for another drug to treat the more common hemophilia A, set a price for Alprolix of $2.85 per international unit. That is more than double the price of about $1.19 per unit for Pfizer Benefix, one of the most widely used treatments for the disorder. Other approved, older hemophilia B products include Rixubis from Baxter International Inc canada goose uk outlet and Mononine from CSL Behring. Canada Goose Jackets
canada goose But while current drugs canada goose clearance sale are typically needed about two to three times a week, Alprolix is taken once a week or every 10 days, Biogen said. The total annual cost can vary widely based on a patient weight, the severity of their canada goose clearance clotting deficiency and other factors. canada goose
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Canada Goose online think it a meaningful advance in a market that hasn seen a significant advance in a decade and a half, said Kingsley, adding that Alprolix should be available to patients early next month. Canada Goose online
canada goose clearance sale Hemophilia is a hereditary disorder that prevents blood from clotting properly due to lack of a clotting factor protein in the blood. Patients with canada goose coats more severe hemophilia require larger and more frequent doses of blood clotting factors. Worldwide, canada goose uk black friday about one in 5,000 men are born with hemophilia A and one in 25,000 men buy canada goose jacket are born with hemophilia B each year. canada goose clearance sale
canada goose deals Denmark Novo Nordisk is also developing a long acting treatment for canada goose coats on sale hemophilia B, and expects to file next year for regulatory approval. canada goose deals
canada goose store Alprolix is a bioengineered version of the Canada Goose https://www.canadagooseoutletstore.co.uk Jackets blood coagulation protein known as factor IX, which is needed for normal blood clotting. If not properly treated, hemophilia can lead to bleeding into joints and muscles that can cause stiffness, pain, severe joint damage, disability, and death canada goose store.